Cargando…

Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson’s disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007)

Mutations in the SNCA (α-synuclein, PARK1) gene significantly contribute to Parkinson’s disease (PD) and SNCA inclusions are strongly associated with PD. Fibroblasts from a 51-year-old female patient with disease onset at 39 years, carrying the A53T SNCA mutation (LCSBi003, ND40996), and fibroblasts...

Descripción completa

Detalles Bibliográficos
Autores principales: Novak, Gabriela, Finkbeiner, Steven, Skibinski, Gaia, Skupin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124237/
https://www.ncbi.nlm.nih.gov/pubmed/34826737
http://dx.doi.org/10.1016/j.scr.2021.102600

Ejemplares similares