Alzheimer‐like tau accumulation in dentate gyrus mossy cells induces spatial cognitive deficits by disrupting multiple memory‐related signaling and inhibiting local neural circuit

Abnormal tau accumulation and spatial memory loss constitute characteristic pathology and symptoms of Alzheimer disease (AD). Yet, the intrinsic connections and the mechanism between them are not fully understood. In the current study, we observed a prominent accumulation of the AD‐like hyperphospho...

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Detalles Bibliográficos
Autores principales: Li, Shihong, Zhou, Qiuzhi, Liu, Enjie, Du, Huiyun, Yu, Nana, Yu, Haitao, Wang, Weijin, Li, Mengzhu, Weng, Ying, Gao, Yang, Pi, Guilin, Wang, Xin, Ke, Dan, Wang, Jian‐Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124302/
https://www.ncbi.nlm.nih.gov/pubmed/35355405
http://dx.doi.org/10.1111/acel.13600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124302/
https://www.ncbi.nlm.nih.gov/pubmed/35355405
http://dx.doi.org/10.1111/acel.13600

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