Cargando…

Amyloid‐β activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk‐AMPK pathway

Neuroinflammation is considered one of major factors in the pathogenesis of Alzheimer's disease (AD). In particular, inflammasome activation, including NLRP3 inflammasome in microglia, is regarded as fundamental for the pro‐inflammatory response of immune cells. However, the precise molecular m...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Eun Sun, Suh, Kyujin, Han, Jihui, Kim, Heyyoung, Kang, Hyung‐Sik, Choi, Won‐Seok, Mook‐Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124305/
https://www.ncbi.nlm.nih.gov/pubmed/35474599
http://dx.doi.org/10.1111/acel.13623

Ejemplares similares