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Amyloid‐β activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk‐AMPK pathway
Neuroinflammation is considered one of major factors in the pathogenesis of Alzheimer's disease (AD). In particular, inflammasome activation, including NLRP3 inflammasome in microglia, is regarded as fundamental for the pro‐inflammatory response of immune cells. However, the precise molecular m...
Autores principales: | Jung, Eun Sun, Suh, Kyujin, Han, Jihui, Kim, Heyyoung, Kang, Hyung‐Sik, Choi, Won‐Seok, Mook‐Jung, Inhee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124305/ https://www.ncbi.nlm.nih.gov/pubmed/35474599 http://dx.doi.org/10.1111/acel.13623 |
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