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Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank

BACKGROUND: The role of copy number variants (CNVs) in susceptibility to asthma is not well understood. This is, in part, due to the difficulty of accurately measuring CNVs in large enough sample sizes to detect associations. The recent availability of whole-exome sequencing (WES) in large biobank s...

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Detalles Bibliográficos
Autores principales:	Fawcett, Katherine A., Demidov, German, Shrine, Nick, Paynton, Megan L., Ossowski, Stephan, Sayers, Ian, Wain, Louise V., Hollox, Edward J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124406/ https://www.ncbi.nlm.nih.gov/pubmed/35597955 http://dx.doi.org/10.1186/s12920-022-01268-y

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