3D reconstructed brain images reveal the possibility of the ogg1 gene to suppress the irradiation-induced apoptosis in embryonic brain in medaka (Oryzias latipes)

The accumulation of oxidative DNA lesions in neurons is associated with neurodegenerative disorders and diseases. Ogg1 (8-oxoG DNA glycosylase-1) is a primary repair enzyme to excise 7,8-dihydro-8-oxoguanine (8-oxoG), the most frequent mutagenic base lesion produced by oxidative DNA damage. We have...

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Detalles Bibliográficos
Autores principales: Yasuda, Takako, Li, Duolin, Sha, Erge, Kakimoto, Fumitaka, Mitani, Hiroshi, Yamamoto, Hiroshi, Ishikawa-Fujiwara, Tomoko, Todo, Takeshi, Oda, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Fundamental Radiation Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124622/
https://www.ncbi.nlm.nih.gov/pubmed/35276012
http://dx.doi.org/10.1093/jrr/rrac005

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