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Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels

Background: Human pentameric ligand-gated ion channels (pLGICs) comprise nicotinic acetylcholine receptors (nAChRs), 5-hydroxytryptamine type 3 receptors (5-HT(3)Rs), zinc-activated channels (ZAC), γ-aminobutyric acid type A receptors (GABA(A)Rs) and glycine receptors (GlyRs). They are recognized th...

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Detalles Bibliográficos
Autores principales:	Koniuszewski, Filip, Vogel, Florian D., Bampali, Konstantina, Fabjan, Jure, Seidel, Thomas, Scholze, Petra, Schmiedhofer, Philip B., Langer, Thierry, Ernst, Margot
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124788/ https://www.ncbi.nlm.nih.gov/pubmed/35615739 http://dx.doi.org/10.3389/fmolb.2022.860246

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