Tetrandrine Citrate Suppresses Breast Cancer via Depletion of Glutathione Peroxidase 4 and Activation of Nuclear Receptor Coactivator 4-Mediated Ferritinophagy

Tetrandrine citrate (TetC), a novel tetrandrine salt with high water solubility, demonstrates a potent antitumor activity in chronic myeloid leukemia. Studies have indicated an important role of ferroptosis in breast cancer (BC). However, whether TetC inhibits BC progression via ferroptosis has neve...

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Detalles Bibliográficos
Autores principales: Yin, Jiameng, Lin, Yajun, Fang, Weiwei, Zhang, Xin, Wei, Jie, Hu, Gang, Liu, Pu, Niu, Jie, Guo, Jun, Zhen, Yongzhan, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124810/
https://www.ncbi.nlm.nih.gov/pubmed/35614944
http://dx.doi.org/10.3389/fphar.2022.820593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124810/
https://www.ncbi.nlm.nih.gov/pubmed/35614944
http://dx.doi.org/10.3389/fphar.2022.820593

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