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Hypothesis: Amelioration of obesity‐induced cognitive dysfunction via a lorcaserin–betahistine combination treatment

The prolonged exposure to obesogenic diets disrupts the mesocortical dopaminergic input to the prefrontal cortex (PFC). This leads to suboptimal dopamine levels in this brain region, which affects cognition and control of food intake. Treatments that restore mesocortical dopaminergic neurotransmissi...

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Detalles Bibliográficos
Autores principales: dela Peña, Ike C., Figueroa, Johnny D., Shi, Wei‐Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124816/
https://www.ncbi.nlm.nih.gov/pubmed/35599337
http://dx.doi.org/10.1002/prp2.947