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Structure-Activity Relationships of Dopamine Transporter Pharmacological Chaperones

Mutations in the dopamine transporter gene (SLC6A3) have been implicated in many human diseases. Among these is the infantile parkinsonism-dystonia known as Dopamine Transporter Deficiency Syndrome (DTDS). Afflicted individuals have minimal to no functional dopamine transporter protein. This is prim...

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Detalles Bibliográficos
Autores principales: Sutton, Charles, Williams, Erin Q., Homsi, Hoomam, Beerepoot, Pieter, Nazari, Reza, Han, Dong, Ramsey, Amy J., Mash, Deborah C., Olson, David E., Blough, Bruce, Salahpour, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124866/
https://www.ncbi.nlm.nih.gov/pubmed/35614973
http://dx.doi.org/10.3389/fncel.2022.832536

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