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Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019

A 26-year-old primipara woman with COVID-19 performed an emergency Cesarean section due to further hypoxemia at 28 weeks 5/7 days gestation. The female neonate was born weighing 1,347 gram with an Apgar score of four at 1 min, three at 5 min, and eight at 10 min. RT-PCR from nasopharyngeal swabs for...

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Autores principales: Kobata, Keisuke, Yutaka, Nanae, Ogasawara, Hiroshi, Mima, Aya, Suzuki, Kaho, Hazama, Ryoichi, Goldman, Ran D., Nabetani, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124962/
https://www.ncbi.nlm.nih.gov/pubmed/35615636
http://dx.doi.org/10.3389/fped.2022.887132
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author Kobata, Keisuke
Yutaka, Nanae
Ogasawara, Hiroshi
Mima, Aya
Suzuki, Kaho
Hazama, Ryoichi
Goldman, Ran D.
Nabetani, Makoto
author_facet Kobata, Keisuke
Yutaka, Nanae
Ogasawara, Hiroshi
Mima, Aya
Suzuki, Kaho
Hazama, Ryoichi
Goldman, Ran D.
Nabetani, Makoto
author_sort Kobata, Keisuke
collection PubMed
description A 26-year-old primipara woman with COVID-19 performed an emergency Cesarean section due to further hypoxemia at 28 weeks 5/7 days gestation. The female neonate was born weighing 1,347 gram with an Apgar score of four at 1 min, three at 5 min, and eight at 10 min. RT-PCR from nasopharyngeal swabs for COVID-19 were performed at birth, 24 h, and 48 h after birth, all of which were negative. On head ultrasound bilateral cystic lesions were found in the anterior horn of the lateral ventricles at birth. A brain magnetic resonance imaging (MRI) test at 56 days of life (corrected 36 weeks and 6/7 days) revealed cystic lesions with T1 low signal, T2 high signal, and T2 Flair high signal around the anterior horn of the lateral ventricle and We diagnose it as Grade 2 periventricular leukomalacia (PVL). She was discharged on day 64 of life, with no abnormality on exam. While the majority of neonates born to women with COVID-19 during pregnancy have favorable outcome, we report a case of a neonate with Grade 2 periventricular leukomalacia and this should prompt clinicians to monitor fetal cerebral function and structure shortly after birth.
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spelling pubmed-91249622022-05-24 Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019 Kobata, Keisuke Yutaka, Nanae Ogasawara, Hiroshi Mima, Aya Suzuki, Kaho Hazama, Ryoichi Goldman, Ran D. Nabetani, Makoto Front Pediatr Pediatrics A 26-year-old primipara woman with COVID-19 performed an emergency Cesarean section due to further hypoxemia at 28 weeks 5/7 days gestation. The female neonate was born weighing 1,347 gram with an Apgar score of four at 1 min, three at 5 min, and eight at 10 min. RT-PCR from nasopharyngeal swabs for COVID-19 were performed at birth, 24 h, and 48 h after birth, all of which were negative. On head ultrasound bilateral cystic lesions were found in the anterior horn of the lateral ventricles at birth. A brain magnetic resonance imaging (MRI) test at 56 days of life (corrected 36 weeks and 6/7 days) revealed cystic lesions with T1 low signal, T2 high signal, and T2 Flair high signal around the anterior horn of the lateral ventricle and We diagnose it as Grade 2 periventricular leukomalacia (PVL). She was discharged on day 64 of life, with no abnormality on exam. While the majority of neonates born to women with COVID-19 during pregnancy have favorable outcome, we report a case of a neonate with Grade 2 periventricular leukomalacia and this should prompt clinicians to monitor fetal cerebral function and structure shortly after birth. Frontiers Media S.A. 2022-05-09 /pmc/articles/PMC9124962/ /pubmed/35615636 http://dx.doi.org/10.3389/fped.2022.887132 Text en Copyright © 2022 Kobata, Yutaka, Ogasawara, Mima, Suzuki, Hazama, Goldman and Nabetani. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Kobata, Keisuke
Yutaka, Nanae
Ogasawara, Hiroshi
Mima, Aya
Suzuki, Kaho
Hazama, Ryoichi
Goldman, Ran D.
Nabetani, Makoto
Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019
title Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019
title_full Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019
title_fullStr Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019
title_full_unstemmed Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019
title_short Case Report: A Very Low Birth Weight Female Infant With Congenital Bilateral Periventricular Leukomalacia, Born to a Mother With Coronavirus Disease 2019
title_sort case report: a very low birth weight female infant with congenital bilateral periventricular leukomalacia, born to a mother with coronavirus disease 2019
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124962/
https://www.ncbi.nlm.nih.gov/pubmed/35615636
http://dx.doi.org/10.3389/fped.2022.887132
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