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ROBO1 p.E280* Loses the Inhibitory Effects on the Proliferation and Angiogenesis of Wild-Type ROBO1 in Cholangiocarcinoma by Interrupting SLIT2 Signal
BACKGROUND: Cholangiocarcinoma (CCA) remains one of the most lethal malignancies with an increasing incidence globally. Through whole-exome sequencing of 67 CCA tissues, we identified new mutated genes in CCA, including MACF1, METTL14, ROBO1, and so on. The study was designed to explore the effects...
Autores principales: | Zhou, Tao, Zhang, Yaodong, Chen, Yananlan, Shan, Jijun, Wang, Jifei, Wang, Yirui, Chang, Jiang, Jiang, Wangjie, Chen, Ruixiang, Wang, Ziyi, Shi, Xiaoli, Yu, Yue, Li, Changxian, Li, Xiangcheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124974/ https://www.ncbi.nlm.nih.gov/pubmed/35615148 http://dx.doi.org/10.3389/fonc.2022.879963 |
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