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Iguratimod Attenuates Macrophage Polarization and Antibody-Mediated Rejection After Renal Transplant by Regulating KLF4

Background: This study aimed to explore the effect and mechanism of iguratimod (IGT) on M1 macrophage polarization and antibody-mediated rejection (ABMR) after renal transplant. Methods: Bioinformatics analysis was performed using three public databases derived from the GEO database. Sprague–Dawley...

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Detalles Bibliográficos
Autores principales: Hang, Zhou, Wei, Jintao, Zheng, Ming, Gui, Zeping, Chen, Hao, Sun, Li, Fei, Shuang, Han, Zhijian, Tao, Jun, Wang, Zijie, Tan, Ruoyun, Gu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125033/
https://www.ncbi.nlm.nih.gov/pubmed/35614941
http://dx.doi.org/10.3389/fphar.2022.865363