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Adoptive Immunotherapy With Engineered iNKT Cells to Target Cancer Cells and the Suppressive Microenvironment

Invariant Natural Killer T (iNKT) cells are T lymphocytes expressing a conserved semi-invariant TCR specific for lipid antigens (Ags) restricted for the monomorphic MHC class I-related molecule CD1d. iNKT cells infiltrate mouse and human tumors and play an important role in the immune surveillance a...

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Detalles Bibliográficos
Autores principales: Delfanti, Gloria, Dellabona, Paolo, Casorati, Giulia, Fedeli, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125179/
https://www.ncbi.nlm.nih.gov/pubmed/35615083
http://dx.doi.org/10.3389/fmed.2022.897750

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