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Endothelial β-Catenin Deficiency Causes Blood-Brain Barrier Breakdown via Enhancing the Paracellular and Transcellular Permeability

Disruption of the blood-brain barrier (BBB) causes or contributes to neuronal dysfunction and several central nervous system (CNS) disorders. Wnt/β-catenin signaling is essential for maintaining the integrity of the adult BBB in physiological and pathological conditions, including stroke. However, h...

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Detalles Bibliográficos
Autores principales: Hussain, Basharat, Fang, Cheng, Huang, Xiaowen, Feng, Ziying, Yao, Yuxuan, Wang, Yu, Chang, Junlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125181/
https://www.ncbi.nlm.nih.gov/pubmed/35615065
http://dx.doi.org/10.3389/fnmol.2022.895429