Cargando…
Primary Leiomyosarcoma of the Glans
Penile leiomyosarcoma isz an extremely uncommon entity that rarely occurs in the glans. Due to the limited number of cases described in literature, guidelines regarding non-surgical treatment, prognosis, and management remain equivocal. Among the mesenchymal tumors of the penis, leiomyosarcoma has t...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125307/ https://www.ncbi.nlm.nih.gov/pubmed/35615157 http://dx.doi.org/10.3389/fonc.2022.851003 |
_version_ | 1784711921228840960 |
---|---|
author | da Costa Junior, Raimundo Nonato Gois Teixeira Júnior, Antonio Augusto Lima Rocha, Thalita Moura Silva Sobrinho, Thaís Bastos Moraes Barbosa, Liseana de Oliveira Silva, Rafael Campos Corrêa, Rita da Graça Carvalhal Frazão Alencar Junior, Antonio Machado Nascimento, Francisco Sergio Moura Silva Melo, Syomara Pereira da Costa Calixto, José Ribamar Rodrigues Silva, Gyl Eanes Barros |
author_facet | da Costa Junior, Raimundo Nonato Gois Teixeira Júnior, Antonio Augusto Lima Rocha, Thalita Moura Silva Sobrinho, Thaís Bastos Moraes Barbosa, Liseana de Oliveira Silva, Rafael Campos Corrêa, Rita da Graça Carvalhal Frazão Alencar Junior, Antonio Machado Nascimento, Francisco Sergio Moura Silva Melo, Syomara Pereira da Costa Calixto, José Ribamar Rodrigues Silva, Gyl Eanes Barros |
author_sort | da Costa Junior, Raimundo Nonato Gois |
collection | PubMed |
description | Penile leiomyosarcoma isz an extremely uncommon entity that rarely occurs in the glans. Due to the limited number of cases described in literature, guidelines regarding non-surgical treatment, prognosis, and management remain equivocal. Among the mesenchymal tumors of the penis, leiomyosarcoma has the highest propensity for recurrence. It originates in the smooth muscle cells from two distinct locations: superficial and deep. The deep subtype is the most aggressive and has the highest potential for metastasis. Surgical treatment should be implemented early and must be locally aggressive. Herein, we present a rare case of a 54-year-old patient with deep localized leiomyosarcoma of the glans, albeit with superficial characteristics. A review of the main histopathological, clinical, immunohistochemical, and therapeutic aspects of this unusual entity is presented. |
format | Online Article Text |
id | pubmed-9125307 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91253072022-05-24 Primary Leiomyosarcoma of the Glans da Costa Junior, Raimundo Nonato Gois Teixeira Júnior, Antonio Augusto Lima Rocha, Thalita Moura Silva Sobrinho, Thaís Bastos Moraes Barbosa, Liseana de Oliveira Silva, Rafael Campos Corrêa, Rita da Graça Carvalhal Frazão Alencar Junior, Antonio Machado Nascimento, Francisco Sergio Moura Silva Melo, Syomara Pereira da Costa Calixto, José Ribamar Rodrigues Silva, Gyl Eanes Barros Front Oncol Oncology Penile leiomyosarcoma isz an extremely uncommon entity that rarely occurs in the glans. Due to the limited number of cases described in literature, guidelines regarding non-surgical treatment, prognosis, and management remain equivocal. Among the mesenchymal tumors of the penis, leiomyosarcoma has the highest propensity for recurrence. It originates in the smooth muscle cells from two distinct locations: superficial and deep. The deep subtype is the most aggressive and has the highest potential for metastasis. Surgical treatment should be implemented early and must be locally aggressive. Herein, we present a rare case of a 54-year-old patient with deep localized leiomyosarcoma of the glans, albeit with superficial characteristics. A review of the main histopathological, clinical, immunohistochemical, and therapeutic aspects of this unusual entity is presented. Frontiers Media S.A. 2022-05-09 /pmc/articles/PMC9125307/ /pubmed/35615157 http://dx.doi.org/10.3389/fonc.2022.851003 Text en Copyright © 2022 Costa Junior, Teixeira Júnior, Rocha, Sobrinho, Barbosa, Silva, Corrêa, Alencar Junior, Nascimento, Melo, Calixto and Silva https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology da Costa Junior, Raimundo Nonato Gois Teixeira Júnior, Antonio Augusto Lima Rocha, Thalita Moura Silva Sobrinho, Thaís Bastos Moraes Barbosa, Liseana de Oliveira Silva, Rafael Campos Corrêa, Rita da Graça Carvalhal Frazão Alencar Junior, Antonio Machado Nascimento, Francisco Sergio Moura Silva Melo, Syomara Pereira da Costa Calixto, José Ribamar Rodrigues Silva, Gyl Eanes Barros Primary Leiomyosarcoma of the Glans |
title | Primary Leiomyosarcoma of the Glans |
title_full | Primary Leiomyosarcoma of the Glans |
title_fullStr | Primary Leiomyosarcoma of the Glans |
title_full_unstemmed | Primary Leiomyosarcoma of the Glans |
title_short | Primary Leiomyosarcoma of the Glans |
title_sort | primary leiomyosarcoma of the glans |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125307/ https://www.ncbi.nlm.nih.gov/pubmed/35615157 http://dx.doi.org/10.3389/fonc.2022.851003 |
work_keys_str_mv | AT dacostajuniorraimundononatogois primaryleiomyosarcomaoftheglans AT teixeirajuniorantonioaugustolima primaryleiomyosarcomaoftheglans AT rochathalitamourasilva primaryleiomyosarcomaoftheglans AT sobrinhothaisbastosmoraes primaryleiomyosarcomaoftheglans AT barbosaliseanadeoliveira primaryleiomyosarcomaoftheglans AT silvarafaelcampos primaryleiomyosarcomaoftheglans AT correaritadagracacarvalhalfrazao primaryleiomyosarcomaoftheglans AT alencarjuniorantoniomachado primaryleiomyosarcomaoftheglans AT nascimentofranciscosergiomourasilva primaryleiomyosarcomaoftheglans AT melosyomarapereiradacosta primaryleiomyosarcomaoftheglans AT calixtojoseribamarrodrigues primaryleiomyosarcomaoftheglans AT silvagyleanesbarros primaryleiomyosarcomaoftheglans |