Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow

OBJECTIVES: This study aims to determine the role and mechanism of autophagy in endothelial cell dysfunction by glucolipotoxicity. METHODS: Human umbilical vein endothelial cells (HUVECs) were treated with high glucose and high palmitic acid. The number of autophagosomes was evaluated by monodansylc...

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Detalles Bibliográficos
Autores principales: Liu, Yulan, Xiang, Hong, Xiong, Wenfang, Ouyang, Jie, Liu, Hengdao, Zhao, Shaoli, Xiao, Jie, Li, Jialing, Shu, Zhihao, Wang, Xuewen, Liu, Huiqin, Zhang, Jing, Fan, Jianing, Li, Ying, Chen, Shuhua, Lu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125420/
https://www.ncbi.nlm.nih.gov/pubmed/35549572
http://dx.doi.org/10.1177/14791641221102513

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