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Alpha- and Gamma-Tocopherol Modulates the Amyloidogenic Pathway of Amyloid Precursor Protein in an in vitro Model of Alzheimer’s Disease: A Transcriptional Study

The amyloid precursor protein (APP) processing pathway was altered in Alzheimer’s disease (AD) and contributed to abnormal amyloid-beta (Aβ) production, which forms insoluble interneuron protein aggregates known as amyloid plaques in the brain. Targeting the APP processing pathway is still fundament...

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Detalles Bibliográficos
Autores principales:	Pahrudin Arrozi, Aslina, Shukri, Siti Nur Syazwani, Mohd Murshid, Nuraqila, Ahmad Shahzalli, Ahmad Baihaqi, Wan Ngah, Wan Zurinah, Ahmad Damanhuri, Hanafi, Makpol, Suzana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125555/ https://www.ncbi.nlm.nih.gov/pubmed/35614968 http://dx.doi.org/10.3389/fncel.2022.846459

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