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Subcellular Propagation of Cardiomyocyte β-Adrenergic Activation of Calcium Uptake Involves Internal β-Receptors and AKAP7

β-adrenergic receptor (β-AR) signaling in cardiac myocytes is central to cardiac function, but spatiotemporal activation within myocytes is unresolved. In rabbit ventricular myocytes, β-AR agonists or high extracellular [Ca] were applied locally at one end, to measure β-AR signal propagation as Ca−t...

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Detalles Bibliográficos
Autores principales: Shannon, Thomas R, Bare, Dan J, Van Dijk, Sabine, Raofi, Shayan, Huynh, Tiffany N-M, Xiang, Yang K, Bossuyt, Julie, Dodge-Kafka, Kimberly L, Ginsburg, Kenneth S, Bers, Donald M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125612/
https://www.ncbi.nlm.nih.gov/pubmed/35620477
http://dx.doi.org/10.1093/function/zqac020