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Efficacy of pembrolizumab in patients with advanced cancer of unknown primary (CUP): a phase 2 non-randomized clinical trial

BACKGROUND: Cancer of unknown primary (CUP) is an aggressive rare malignancy with limited treatment options. Data regarding clinical activity of immune checkpoint inhibitors in CUP is lacking. Therefore, we evaluated the efficacy of pembrolizumab, a programmed cell death-1 inhibitor, in patients wit...

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Detalles Bibliográficos
Autores principales: Raghav, Kanwal P, Stephen, Bettzy, Karp, Daniel D, Piha-Paul, Sarina A, Hong, David S, Jain, Dipti, Chudy Onwugaje, Dilichukwu O, Abonofal, Abdulrahman, Willett, Anneleis F, Overman, Michael, Smaglo, Brandon, Huey, Ryan W, Meric-Bernstam, Funda, Varadhachary, Gauri R, Naing, Aung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125753/
https://www.ncbi.nlm.nih.gov/pubmed/35618285
http://dx.doi.org/10.1136/jitc-2022-004822