Early and progressive dysfunction revealed by in vivo neurite imaging in the rNLS8 TDP-43 mouse model of ALS

Amyotrophic lateral sclerosis (ALS) is characterized by transactive response DNA-binding protein 43 (TDP-43) pathology, progressive loss of motor neurons and muscle dysfunction. Symptom onset can be insidious and diagnosis challenging. Conventional neuroimaging is used to exclude ALS mimics, however...

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Detalles Bibliográficos
Autores principales: Zamani, Akram, Walker, Adam K., Rollo, Ben, Ayers, Katie L., Farah, Raysha, O'Brien, Terence J., Wright, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles from the Special Issue on "Neuroimaging Approaches in Amyotrophic Lateral Sclerosis (ALS)" Edited by Corey McMillan, Federica Agosta, Martin Turner, Peter Bede and Julian Grosskreutz
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125783/
https://www.ncbi.nlm.nih.gov/pubmed/35483133
http://dx.doi.org/10.1016/j.nicl.2022.103016

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