Cargando…

Mass spectrometry-based proteomics identify novel serum osteoarthritis biomarkers

BACKGROUND: Osteoarthritis (OA) is a slowly developing and debilitating disease, and there are no validated specific biomarkers for its early detection. To improve therapeutic approaches, identification of specific molecules/biomarkers enabling early determination of this disease is needed. This stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tardif, Ginette, Paré, Frédéric, Gotti, Clarisse, Roux-Dalvai, Florence, Droit, Arnaud, Zhai, Guangju, Sun, Guang, Fahmi, Hassan, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125906/ https://www.ncbi.nlm.nih.gov/pubmed/35606786 http://dx.doi.org/10.1186/s13075-022-02801-1

Ejemplares similares

In vivo protective effect of adipsin-deficiency on spontaneous knee osteoarthritis in aging mice
por: Paré, Frédéric, et al.
Publicado: (2020)

NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis
por: Tardif, Ginette, et al.
Publicado: (2013)

Common Biochemical and Magnetic Resonance Imaging Biomarkers of Early Knee Osteoarthritis and of Exercise/Training in Athletes: A Narrative Review
por: Martel-Pelletier, Johanne, et al.
Publicado: (2021)

DIA proteomics data from a UPS1-spiked E.coli protein mixture processed with six software tools
por: Gotti, Clarisse, et al.
Publicado: (2022)

Serum adipokines/related inflammatory factors and ratios as predictors of infrapatellar fat pad volume in osteoarthritis: Applying comprehensive machine learning approaches
por: Bonakdari, Hossein, et al.
Publicado: (2020)

A warning machine learning algorithm for early knee osteoarthritis structural progressor patient screening
por: Bonakdari, Hossein, et al.
Publicado: (2021)

L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis
por: Ouhaddi, Yassine, et al.
Publicado: (2020)

Mesenchymal Stromal Cell Immunology for Efficient and Safe Treatment of Osteoarthritis
por: Najar, Mehdi, et al.
Publicado: (2020)

The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target
por: Li, Ying-Hua, et al.
Publicado: (2016)

Serum lysophosphatidylcholines to phosphatidylcholines ratio is associated with symptomatic responders to symptomatic drugs in knee osteoarthritis patients
por: Zhai, Guangju, et al.
Publicado: (2019)

Identification of the most important features of knee osteoarthritis structural progressors using machine learning methods
por: Jamshidi, Afshin, et al.
Publicado: (2020)

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes
por: Tardif, Ginette, et al.
Publicado: (2009)

Activation of The Phosphatidylcholine to Lysophosphatidylcholine Pathway Is Associated with Osteoarthritis Knee Cartilage Volume Loss Over Time
por: Zhai, Guangju, et al.
Publicado: (2019)

Proteomic Analysis of Maternal Urine for the Early Detection of Preeclampsia and Fetal Growth Restriction
por: Bujold, Emmanuel, et al.
Publicado: (2021)

Enhancing Classification of liquid chromatography mass spectrometry data with Batch Effect Removal Neural Networks (BERNN)
por: Droit, Arnaud, et al.
Publicado: (2023)

Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis
por: Chabane, Nadir, et al.
Publicado: (2009)

Implication of microRNA-140 in osteoarthritis
por: Martel-Pelletier, Johanne
Publicado: (2012)

Integrative analysis of green ash phloem transcripts and proteins during an emerald ash borer infestation
por: Chiu, Christine C., et al.
Publicado: (2023)

Fast and Accurate Bacterial Species Identification in Urine Specimens Using LC-MS/MS Mass Spectrometry and Machine Learning
por: Roux-Dalvai, Florence, et al.
Publicado: (2019)

The Novartis-ILAR Rheumatology Prize 2001 Osteoarthritis: from molecule to man
por: Pelletier, Jean-Pierre, et al.
Publicado: (2002)

Expression of PPARα, β, and γ in the Hartley guinea pig model of primary osteoarthritis
por: Ezzahra El Mansouri, Fatima, et al.
Publicado: (2012)

Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site
por: Monfort, Jordi, et al.
Publicado: (2006)

Correction: Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease 13 - identification of a new biglycan cleavage site
por: Monfort, Jordi, et al.
Publicado: (2013)

Novel insights for improving the therapeutic safety and efficiency of mesenchymal stromal cells
por: Najar, Mehdi, et al.
Publicado: (2020)

Is there a mitochondrial DNA haplogroup connection between osteoarthritis and elite athletes? A narrative review
por: Martel-Pelletier, Johanne, et al.
Publicado: (2022)

Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study
por: Tat, Steeve Kwan, et al.
Publicado: (2007)

In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis
por: Farrán, Aina, et al.
Publicado: (2018)

Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells
por: Sheta, Razan, et al.
Publicado: (2016)

Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow
por: Pelletier, Jean-Pierre, et al.
Publicado: (2006)

Magnetic resonance imaging assessments for knee segmentation and their use in combination with machine/deep learning as predictors of early osteoarthritis diagnosis and prognosis
por: Martel-Pelletier, Johanne, et al.
Publicado: (2023)

Cartilage-specific deletion of prar-gamma in mice results in early endochondral ossification defects and accelerated aging-dependent development of osteoarthritis
por: Monemdjou, Roxana, et al.
Publicado: (2012)

Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo
por: Valverde-Franco, Gladys, et al.
Publicado: (2016)

Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study
por: Boileau, Christelle, et al.
Publicado: (2007)

Abnormal osteogenesis in osteoarthritis: gone with the Wnt?
por: Lajeunesse, Daniel, et al.
Publicado: (2012)

Impact of oral osteoarthritis therapy usage among other risk factors on knee replacement: a nested case-control study using the Osteoarthritis Initiative cohort
por: Dorais, Marc, et al.
Publicado: (2018)

A Machine Learning Model to Predict Knee Osteoarthritis Cartilage Volume Changes over Time Using Baseline Bone Curvature
por: Bonakdari, Hossein, et al.
Publicado: (2022)

Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein
por: Aumailley, Lucie, et al.
Publicado: (2018)

Peroxisome proliferator-activated receptor gamma 1 expression is diminished in human osteoarthritis cartilage and is downregulated by IL-1β in articular chondrocytes
por: Afif, H, et al.
Publicado: (2007)

Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes
por: Afif, Hassan, et al.
Publicado: (2007)

Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis: 9-year follow-up data from the Osteoarthritis Initiative
por: Pelletier, Jean-Pierre, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dokdg2hggvn0s918bv9i55jbkr