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NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway

Periprosthetic osteolysis (PPO) triggered by wear particles is the most severe complication of total joint replacement (TJR) surgeries, representing the major cause of implant failure, which is public health concern worldwide. Previous studies have confirmed the specialized role of osteoclast-induce...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Liang, Xiaolong, Liu, Xin, Bai, Jiaxiang, Zhang, Wei, Li, Wenming, Wang, Tianhao, Li, Meng, Wu, Zerui, Chen, Liang, Yang, Huilin, Gu, Ye, Tao, Yunxia, Zhou, Jun, Wang, Huaiyu, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125939/
https://www.ncbi.nlm.nih.gov/pubmed/35606794
http://dx.doi.org/10.1186/s12951-022-01413-w