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Molecular Taxonomy of Systemic Lupus Erythematosus Through Data-Driven Patient Stratification: Molecular Endotypes and Cluster-Tailored Drugs

OBJECTIVES: Treatment of Systemic Lupus Erythematosus (SLE) is characterized by a largely empirical approach and relative paucity of novel compound development. We sought to stratify SLE patients based on their molecular phenotype and identify putative therapeutic compounds for each molecular finger...

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Detalles Bibliográficos
Autores principales: Garantziotis, Panagiotis, Nikolakis, Dimitrios, Doumas, Stavros, Frangou, Eleni, Sentis, George, Filia, Anastasia, Fanouriakis, Antonis, Bertsias, George, Boumpas, Dimitrios T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125979/
https://www.ncbi.nlm.nih.gov/pubmed/35615355
http://dx.doi.org/10.3389/fimmu.2022.860726