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The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study
Rabies is a fatal disease that has been a serious health concern, especially in developing countries. Although rabies is preventable by vaccination, the spread still occurs sporadically in many countries, including Thailand. Geographical structures, habitats, and behaviors of host populations are es...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126089/ https://www.ncbi.nlm.nih.gov/pubmed/35536861 http://dx.doi.org/10.1371/journal.pntd.0010397 |
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author | Sararat, Chayanin Changruenngam, Suttikiat Chumkaeo, Arun Wiratsudakul, Anuwat Pan-ngum, Wirichada Modchang, Charin |
author_facet | Sararat, Chayanin Changruenngam, Suttikiat Chumkaeo, Arun Wiratsudakul, Anuwat Pan-ngum, Wirichada Modchang, Charin |
author_sort | Sararat, Chayanin |
collection | PubMed |
description | Rabies is a fatal disease that has been a serious health concern, especially in developing countries. Although rabies is preventable by vaccination, the spread still occurs sporadically in many countries, including Thailand. Geographical structures, habitats, and behaviors of host populations are essential factors that may result in an enormous impact on the mechanism of propagation and persistence of the disease. To investigate the role of geographical structures on the transmission dynamics of canine rabies, we developed a stochastic individual-based model that integrates the exact configuration of buildings and roads. In our model, the spatial distribution of dogs was estimated based on the distribution of buildings, with roads considered to facilitate dog movement. Two contrasting areas with high- and low-risk of rabies transmission in Thailand, namely, Hatyai and Tepha districts, were chosen as study sites. Our modeling results indicated that the distinct geographical structures of buildings and roads in Hatyai and Tepha could contribute to the difference in the rabies transmission dynamics in these two areas. The high density of buildings and roads in Hatyai could facilitate more rabies transmission. We also investigated the impacts of rabies intervention, including reducing the dog population, restricting owned dog movement, and dog vaccination on the spread of canine rabies in these two areas. We found that reducing the dog population alone might not be sufficient for preventing rabies transmission in the high-risk area. Owned dog confinement could reduce more the likelihood of rabies transmission. Finally, a higher vaccination coverage may be required for controlling rabies transmission in the high-risk area compared to the low-risk area. |
format | Online Article Text |
id | pubmed-9126089 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-91260892022-05-24 The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study Sararat, Chayanin Changruenngam, Suttikiat Chumkaeo, Arun Wiratsudakul, Anuwat Pan-ngum, Wirichada Modchang, Charin PLoS Negl Trop Dis Research Article Rabies is a fatal disease that has been a serious health concern, especially in developing countries. Although rabies is preventable by vaccination, the spread still occurs sporadically in many countries, including Thailand. Geographical structures, habitats, and behaviors of host populations are essential factors that may result in an enormous impact on the mechanism of propagation and persistence of the disease. To investigate the role of geographical structures on the transmission dynamics of canine rabies, we developed a stochastic individual-based model that integrates the exact configuration of buildings and roads. In our model, the spatial distribution of dogs was estimated based on the distribution of buildings, with roads considered to facilitate dog movement. Two contrasting areas with high- and low-risk of rabies transmission in Thailand, namely, Hatyai and Tepha districts, were chosen as study sites. Our modeling results indicated that the distinct geographical structures of buildings and roads in Hatyai and Tepha could contribute to the difference in the rabies transmission dynamics in these two areas. The high density of buildings and roads in Hatyai could facilitate more rabies transmission. We also investigated the impacts of rabies intervention, including reducing the dog population, restricting owned dog movement, and dog vaccination on the spread of canine rabies in these two areas. We found that reducing the dog population alone might not be sufficient for preventing rabies transmission in the high-risk area. Owned dog confinement could reduce more the likelihood of rabies transmission. Finally, a higher vaccination coverage may be required for controlling rabies transmission in the high-risk area compared to the low-risk area. Public Library of Science 2022-05-10 /pmc/articles/PMC9126089/ /pubmed/35536861 http://dx.doi.org/10.1371/journal.pntd.0010397 Text en © 2022 Sararat et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Sararat, Chayanin Changruenngam, Suttikiat Chumkaeo, Arun Wiratsudakul, Anuwat Pan-ngum, Wirichada Modchang, Charin The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study |
title | The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study |
title_full | The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study |
title_fullStr | The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study |
title_full_unstemmed | The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study |
title_short | The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study |
title_sort | effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: an individual-based modeling study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126089/ https://www.ncbi.nlm.nih.gov/pubmed/35536861 http://dx.doi.org/10.1371/journal.pntd.0010397 |
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