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Challenges in the use of sortase and other peptide ligases for site-specific protein modification
Site-specific protein modification is a widely-used biochemical tool. However, there are many challenges associated with the development of protein modification techniques, in particular, achieving site-specificity, reaction efficiency and versatility. The engineering of peptide ligases and their su...
Autores principales: | Morgan, Holly E., Turnbull, W. Bruce, Webb, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126251/ https://www.ncbi.nlm.nih.gov/pubmed/35510539 http://dx.doi.org/10.1039/d0cs01148g |
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