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Challenges in the use of sortase and other peptide ligases for site-specific protein modification

Site-specific protein modification is a widely-used biochemical tool. However, there are many challenges associated with the development of protein modification techniques, in particular, achieving site-specificity, reaction efficiency and versatility. The engineering of peptide ligases and their su...

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Detalles Bibliográficos
Autores principales: Morgan, Holly E., Turnbull, W. Bruce, Webb, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126251/
https://www.ncbi.nlm.nih.gov/pubmed/35510539
http://dx.doi.org/10.1039/d0cs01148g

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