Macrophage ALDH2 (Aldehyde Dehydrogenase 2) Stabilizing Rac2 Is Required for Efferocytosis Internalization and Reduction of Atherosclerosis Development

BACKGROUND: Clinical studies show that the most common single-point mutation in humans, ALDH2 (aldehyde dehydrogenase 2) rs671 mutation, is a risk factor for the development and poor prognosis of atherosclerotic cardiovascular diseases, but the underlying mechanism remains unclear. Apoptotic cells a...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Zhao, Xiangkai, Guo, Yunyun, Liu, Zhiping, Wei, Shujian, Yuan, Qiuhuan, Shang, Haixia, Sang, Wentao, Cui, Sumei, Xu, Tonghui, Yang, Kehui, Guo, Jialin, Pan, Chang, Wang, Jiali, Pang, Jiaojiao, Han, Tianrui, Chen, Yuguo, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126264/
https://www.ncbi.nlm.nih.gov/pubmed/35354308
http://dx.doi.org/10.1161/ATVBAHA.121.317204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126264/
https://www.ncbi.nlm.nih.gov/pubmed/35354308
http://dx.doi.org/10.1161/ATVBAHA.121.317204

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