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Hepatic hormone FGF21 and its analogues in clinical trials

Fibroblast growth factor 21 (FGF21) is a fasting or stress inducible metabolic hormone produced mainly in the liver. It plays important roles in regulating both glucose and lipid homeostasis via interacting with a heterodimeric receptor complex comprising FGF receptor 1 (FGFR1) and β‐klotho (KLB). F...

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Detalles Bibliográficos
Autores principales: Shao, Weijuan, Jin, Tianru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126297/
https://www.ncbi.nlm.nih.gov/pubmed/35620160
http://dx.doi.org/10.1016/j.cdtm.2021.08.005