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Genome‐wide gain‐of‐function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma

Phosphoinositide‐3 kinase alpha (PI3Kα) has been confirmed to be a potential therapeutic target for esophageal squamous cell carcinoma (ESCC), while the potency of PI3Kα inhibitors is often attenuated by concurrent oncogenic signalling pathways. We performed genome‐wide gain‐of‐function screening wi...

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Detalles Bibliográficos
Autores principales:	Xing, Hui, Gao, Mengshi, Wang, Yuxiang, Zhang, Xu, Shi, Jiajie, Wang, Xiang, Liu, Xueling, Ma, Qingyang, Kong, Xiangyin, Yang, Chunhao, Ding, Jian, Meng, Linghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126361/ https://www.ncbi.nlm.nih.gov/pubmed/35604910 http://dx.doi.org/10.1002/ctm2.835

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