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Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination

The COVID-19 pandemic shows that vaccination strategies building on an ancestral viral strain need to be optimized for the control of potentially emerging viral variants. Therefore, aiming at strong B cell somatic hypermutation to increase antibody affinity to the ancestral strain - not only at high...

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Detalles Bibliográficos
Autores principales:	Paschold, Lisa, Klee, Bianca, Gottschick, Cornelia, Willscher, Edith, Diexer, Sophie, Schultheiß, Christoph, Simnica, Donjete, Sedding, Daniel, Girndt, Matthias, Gekle, Michael, Mikolajczyk, Rafael, Binder, Mascha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126551/ https://www.ncbi.nlm.nih.gov/pubmed/35615365 http://dx.doi.org/10.3389/fimmu.2022.876306

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