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Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention

BACKGROUND/OBJECTIVES/INTRODUCTION: It is imperative to accurately estimate whole body fat percentage (%fat) to understand the deleterious nature of excess adiposity on cardiometabolic disease risk. Cost and accessibility often preclude the use of advanced imaging methods like dual-energy X-ray abso...

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Autores principales: Senkus, Katelyn E., Crowe-White, Kristi M., Locher, Julie L., Ard, Jamy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126590/
https://www.ncbi.nlm.nih.gov/pubmed/35471192
http://dx.doi.org/10.1080/07853890.2022.2067352
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author Senkus, Katelyn E.
Crowe-White, Kristi M.
Locher, Julie L.
Ard, Jamy D.
author_facet Senkus, Katelyn E.
Crowe-White, Kristi M.
Locher, Julie L.
Ard, Jamy D.
author_sort Senkus, Katelyn E.
collection PubMed
description BACKGROUND/OBJECTIVES/INTRODUCTION: It is imperative to accurately estimate whole body fat percentage (%fat) to understand the deleterious nature of excess adiposity on cardiometabolic disease risk. Cost and accessibility often preclude the use of advanced imaging methods like dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI). Relative fat mass (RFM) is an emerging estimator of whole body %fat based on waist circumference, height, and biological sex. The purpose of this ancillary study was to examine the relationship between RFM and gold-standard measures of adiposity among community-dwelling older adults with obesity and to evaluate if changes in RFM reflect changes in %fat following a 12-month lifestyle intervention (clinicaltrials.gov #NCT00955903). PATIENTS/MATERIALS AND METHODS: Participants (N = 163, 37.4% male, 70.3 ± 4.7 years) were randomized to the exercise only group, exercise + nutrient-dense weight maintenance group, or exercise + nutrient-dense energy restriction of 500 kcal/d group. Total and regional adiposity assessed by DXA and MRI, as well as anthropometrics, were evaluated at baseline and 12 months. RESULTS: RFM was significantly positively correlated with DXA whole body %fat and DXA trunk %fat at baseline. Equivalence testing revealed that RFM was considered equivalent to DXA whole body %fat for females only. Additionally, from baseline to 12 months, a significant reduction in RFM was observed among female participants in the exercise + energy restriction group only. Changes in RFM were significantly correlated with changes in DXA whole body %fat, DXA trunk fat, and total abdominal fat tissue determined by MRI. CONCLUSION: KEY MESSAGES: Relative fat mass (RFM), an emerging estimator of whole body %fat based on waist circumference, height, and biological sex, was intentionally developed to be a simple estimate of adiposity that overcomes limitations of measures like body mass index. In the current study, results from correlations and agreement analyses support the use of RFM to estimate whole-body fat percentage in a community-dwelling older adult population with obesity when advanced methods, namely dual-energy X-ray absorptiometry, are not feasible. Significant reductions in RFM were also observed over a 12-month period that was significantly correlated with changes in whole body fat percentage; thus, supporting the sensitivity of RFM to lifestyle changes.
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spelling pubmed-91265902022-05-24 Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention Senkus, Katelyn E. Crowe-White, Kristi M. Locher, Julie L. Ard, Jamy D. Ann Med Nutrition BACKGROUND/OBJECTIVES/INTRODUCTION: It is imperative to accurately estimate whole body fat percentage (%fat) to understand the deleterious nature of excess adiposity on cardiometabolic disease risk. Cost and accessibility often preclude the use of advanced imaging methods like dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI). Relative fat mass (RFM) is an emerging estimator of whole body %fat based on waist circumference, height, and biological sex. The purpose of this ancillary study was to examine the relationship between RFM and gold-standard measures of adiposity among community-dwelling older adults with obesity and to evaluate if changes in RFM reflect changes in %fat following a 12-month lifestyle intervention (clinicaltrials.gov #NCT00955903). PATIENTS/MATERIALS AND METHODS: Participants (N = 163, 37.4% male, 70.3 ± 4.7 years) were randomized to the exercise only group, exercise + nutrient-dense weight maintenance group, or exercise + nutrient-dense energy restriction of 500 kcal/d group. Total and regional adiposity assessed by DXA and MRI, as well as anthropometrics, were evaluated at baseline and 12 months. RESULTS: RFM was significantly positively correlated with DXA whole body %fat and DXA trunk %fat at baseline. Equivalence testing revealed that RFM was considered equivalent to DXA whole body %fat for females only. Additionally, from baseline to 12 months, a significant reduction in RFM was observed among female participants in the exercise + energy restriction group only. Changes in RFM were significantly correlated with changes in DXA whole body %fat, DXA trunk fat, and total abdominal fat tissue determined by MRI. CONCLUSION: KEY MESSAGES: Relative fat mass (RFM), an emerging estimator of whole body %fat based on waist circumference, height, and biological sex, was intentionally developed to be a simple estimate of adiposity that overcomes limitations of measures like body mass index. In the current study, results from correlations and agreement analyses support the use of RFM to estimate whole-body fat percentage in a community-dwelling older adult population with obesity when advanced methods, namely dual-energy X-ray absorptiometry, are not feasible. Significant reductions in RFM were also observed over a 12-month period that was significantly correlated with changes in whole body fat percentage; thus, supporting the sensitivity of RFM to lifestyle changes. Taylor & Francis 2022-04-26 /pmc/articles/PMC9126590/ /pubmed/35471192 http://dx.doi.org/10.1080/07853890.2022.2067352 Text en © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Nutrition
Senkus, Katelyn E.
Crowe-White, Kristi M.
Locher, Julie L.
Ard, Jamy D.
Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention
title Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention
title_full Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention
title_fullStr Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention
title_full_unstemmed Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention
title_short Relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention
title_sort relative fat mass assessment estimates changes in adiposity among female older adults with obesity after a 12-month exercise and diet intervention
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126590/
https://www.ncbi.nlm.nih.gov/pubmed/35471192
http://dx.doi.org/10.1080/07853890.2022.2067352
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