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Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics

OBJECTIVES: Endothelin-1 (ET-1), the most potent endogenous vasoconstrictor, generated by enzymatic cleavage catalyzed by an endothelin-converting enzyme (ECE), plays a significant role in the regulation of hypertension. METHODS: This study investigates the effect of endothelin-1 (Lys198Asn/rs5370)...

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Detalles Bibliográficos
Autores principales: Salim, Elnaz, Ramachandran, Vasudevan, Ansari, Neda, Ismail, Patimah, Mohamed, Mohd Hazmi, Mohamad, Nur Afiqah, Inche Mat, Liyana Najwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126669/
https://www.ncbi.nlm.nih.gov/pubmed/35645613
http://dx.doi.org/10.1155/2022/9129960