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Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia

Low levels of high density lipoprotein-cholesterol (HDL-C) are associated with an elevated risk of arteriosclerotic coronary heart disease. Heritability of HDL-C levels is high. In this research discovery study, we used whole-exome sequencing to identify damaging gene variants that may play signific...

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Detalles Bibliográficos
Autores principales:	Dong, Weilai, Wong, Karen H.Y., Liu, Youbin, Levy-Sakin, Michal, Hung, Wei-Chien, Li, Mo, Li, Boyang, Jin, Sheng Chih, Choi, Jungmin, Lopez-Giraldez, Francesc, Vaka, Dedeepya, Poon, Annie, Chu, Catherine, Lao, Richard, Balamir, Melek, Movsesyan, Irina, Malloy, Mary J., Zhao, Hongyu, Kwok, Pui-Yan, Kane, John P., Lifton, Richard P., Pullinger, Clive R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126845/ https://www.ncbi.nlm.nih.gov/pubmed/35460704 http://dx.doi.org/10.1016/j.jlr.2022.100209

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