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The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands

Muscarinic acetylcholine receptors (mAChRs) respond to the neurotransmitter acetylcholine and play important roles in human nervous system. Muscarinic receptor 4 (M4R) is a promising drug target for treating neurological and mental disorders, such as Alzheimer’s disease and schizophrenia. However, t...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Wu, Meng, Chen, Zhangcheng, Wu, Lijie, Wang, Tian, Cao, Dongmei, Wang, Huan, Liu, Shenhui, Xu, Yueming, Li, Fei, Liu, Junlin, Chen, Na, Zhao, Suwen, Cheng, Jianjun, Wang, Sheng, Hua, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126879/
https://www.ncbi.nlm.nih.gov/pubmed/35606397
http://dx.doi.org/10.1038/s41467-022-30595-y