Transfer of microRNA-22-3p by M2 macrophage-derived extracellular vesicles facilitates the development of ankylosing spondylitis through the PER2-mediated Wnt/β-catenin axis

Pathological osteogenesis and inflammation possess critical significance in ankylosing spondylitis (AS). The current study aimed to elucidate the mechanisms regarding extracellular vesicle (EV)-packaged microRNA-22-3p (miR-22-3p) from M2 macrophages in the osteogenic differentiation of mesenchymal s...

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Detalles Bibliográficos
Autores principales: Liu, Chong, Liang, Tuo, Zhang, Zide, Chen, Jiarui, Xue, Jang, Zhan, Xinli, Ren, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126881/
https://www.ncbi.nlm.nih.gov/pubmed/35606376
http://dx.doi.org/10.1038/s41420-022-00900-1

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