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Self-derived peptides from the SARS-CoV-2 spike glycoprotein disrupting shaping and stability of the homotrimer unit

The structural spike (S) protein from the SARS-CoV-2 β-coronavirus is shown to make different pre- and post-fusion conformations within its homotrimer unit. To support the ongoing novel vaccine design and development strategies, we report the structure-based design approach to develop self-derived S...

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Detalles Bibliográficos
Autores principales:	Padariya, Monikaben, Daniels, Alison, Tait-Burkard, Christine, Hupp, Ted, Kalathiya, Umesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier Masson SAS. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127142/ https://www.ncbi.nlm.nih.gov/pubmed/35643065 http://dx.doi.org/10.1016/j.biopha.2022.113190

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