Streamlining the Transition From Yeast Surface Display of Antibody Fragment Immune Libraries to the Production as IgG Format in Mammalian Cells

Yeast-surface display (YSD) is commonly applied to screen Fab immune or naïve libraries for binders of predefined target molecules. However, reformatting of isolated variants represents a time-intensive bottleneck. Herein, we present a novel approach to facilitate a lean transition from antibody scr...

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Detalles Bibliográficos
Autores principales: Fiebig, David, Bogen, Jan P., Carrara, Stefania C., Deweid, Lukas, Zielonka, Stefan, Grzeschik, Julius, Hock, Björn, Kolmar, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127228/
https://www.ncbi.nlm.nih.gov/pubmed/35620472
http://dx.doi.org/10.3389/fbioe.2022.794389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127228/
https://www.ncbi.nlm.nih.gov/pubmed/35620472
http://dx.doi.org/10.3389/fbioe.2022.794389

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