Design Principles of the Rotary Type 9 Secretion System

The F(o) ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors. In this review, we summarize the current information on the nuts and bolts of T9SS. Torque generation by T9SS, its role in g...

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Detalles Bibliográficos
Autores principales: Trivedi, Abhishek, Gosai, Jitendrapuri, Nakane, Daisuke, Shrivastava, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127263/
https://www.ncbi.nlm.nih.gov/pubmed/35620107
http://dx.doi.org/10.3389/fmicb.2022.845563
Descripción
Sumario:The F(o) ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors. In this review, we summarize the current information on the nuts and bolts of T9SS. Torque generation by T9SS, its role in gliding motility of bacteria, and the mechanism via which a T9SS-driven swarm shapes the microbiota are discussed. The knowledge gaps in our current understanding of the T9SS machinery are outlined.

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