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Roxadustat, a Hypoxia-Inducible Factor 1α Activator, Attenuates Both Long- and Short-Term Alcohol-Induced Alcoholic Liver Disease
Alcoholic liver disease (ALD) is a worldwide healthcare problem featured by inflammation, reactive oxygen species (ROS), and lipid dysregulation. Roxadustat is used for chronic kidney disease anemia treatment. As a specific inhibitor of prolyl hydroxylase, it can maintain high levels of hypoxia-indu...
Autores principales: | Gao, Yongyao, Jiang, Xiaomeng, Yang, Daigang, Guo, Wentong, Wang, Dandan, Gong, Ke, Peng, Ying, Jiang, Hong, Shi, Cunyuan, Duan, Yajun, Chen, Yuanli, Han, Jihong, Yang, Xiaoxiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127324/ https://www.ncbi.nlm.nih.gov/pubmed/35620283 http://dx.doi.org/10.3389/fphar.2022.895710 |
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