Complement Factor I Variants in Complement-Mediated Renal Diseases

C3 glomerulopathy (C3G) and atypical hemolytic uremic syndrome (aHUS) are two rare diseases caused by dysregulated activity of the alternative pathway of complement secondary to the presence of genetic and/or acquired factors. Complement factor I (FI) is a serine protease that downregulates compleme...

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Detalles Bibliográficos
Autores principales: Zhang, Yuzhou, Goodfellow, Renee X., Ghiringhelli Borsa, Nicolo, Dunlop, Hannah C., Presti, Stephen A., Meyer, Nicole C., Shao, Dingwu, Roberts, Sarah M., Jones, Michael B., Pitcher, Gabriella R., Taylor, Amanda O., Nester, Carla M., Smith, Richard J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127439/
https://www.ncbi.nlm.nih.gov/pubmed/35619721
http://dx.doi.org/10.3389/fimmu.2022.866330

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