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Difference in PaO(2)/FiO(2) between high-flow nasal cannula and Venturi mask in hypoxemic COVID-19 patients

The ratio between arterial blood partial pressure of oxygen and fraction of inspired oxygen (PaO(2)/FiO(2)) was largely used for grading and managing the respiratory failure in non-mechanically ventilated COVID-19. In these patients, the assessment of the true FiO(2) in the inspired mixture may be d...

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Detalles Bibliográficos
Autores principales: Gatto, Ilenia, Biagioni, Emanuela, Coloretti, Irene, Viappiani, Serena, Busani, Stefano, Girardis, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127475/
https://www.ncbi.nlm.nih.gov/pubmed/37386653
http://dx.doi.org/10.1186/s44158-022-00051-w
Descripción
Sumario:The ratio between arterial blood partial pressure of oxygen and fraction of inspired oxygen (PaO(2)/FiO(2)) was largely used for grading and managing the respiratory failure in non-mechanically ventilated COVID-19. In these patients, the assessment of the true FiO(2) in the inspired mixture may be difficult with consequent inaccuracies in PaO(2)/FiO(2) assessment. In 30 severe COVID-19 patients, we observed that PaO(2)/FiO(2) values measured immediately before and after the transition from high-flow nasal cannula (HFNC) to one commercially available Venturi mask O(2) therapy were similar (bias mean value 0, standard deviation 23 mmHg). In COVID-19 patients recovering from respiratory failure, PaO(2)/FiO(2) is not different whether measured with a commercially available Venturi mask or HFNC.