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Histone chaperone ASF1 acts with RIF1 to promote DNA end joining in BRCA1-deficient cells
Replication timing regulatory factor 1 (RIF1) acts downstream of p53-binding protein 53BP1 to inhibit the resection of DNA broken ends, which plays critical roles in determining the DNA double-strand break repair pathway choice between nonhomologous end joining and homologous recombination (HR). How...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127577/ https://www.ncbi.nlm.nih.gov/pubmed/35472331 http://dx.doi.org/10.1016/j.jbc.2022.101979 |