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Histone chaperone ASF1 acts with RIF1 to promote DNA end joining in BRCA1-deficient cells

Replication timing regulatory factor 1 (RIF1) acts downstream of p53-binding protein 53BP1 to inhibit the resection of DNA broken ends, which plays critical roles in determining the DNA double-strand break repair pathway choice between nonhomologous end joining and homologous recombination (HR). How...

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Detalles Bibliográficos
Autores principales: Tang, Mengfan, Chen, Zhen, Wang, Chao, Feng, Xu, Lee, Namsoo, Huang, Min, Zhang, Huimin, Li, Siting, Xiong, Yun, Chen, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127577/
https://www.ncbi.nlm.nih.gov/pubmed/35472331
http://dx.doi.org/10.1016/j.jbc.2022.101979

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