αα-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes

Formation of transcription factor (TF)–coregulator complexes is a key step in transcriptional regulation, with coregulators having essential functions as hub nodes in molecular networks. How specificity and selectivity are maintained in these nodes remain open questions. In this work, we addressed s...

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Detalles Bibliográficos
Autores principales: Friis Theisen, Frederik, Salladini, Edoardo, Davidsen, Rikke, Jo Rasmussen, Christina, Staby, Lasse, Kragelund, Birthe B., Skriver, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127584/
https://www.ncbi.nlm.nih.gov/pubmed/35452682
http://dx.doi.org/10.1016/j.jbc.2022.101963

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