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Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy

Xylooligosaccharides (XOS) are functional feed additives that are attracting growing commercial interest owing to their excellent ability to modulate the composition of the gut microbiota. The acid hydrolysis-based processing of xylan-containing materials has been proposed to represent a cost-effect...

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Autores principales: Jiang, Kankan, Fu, Xiaoliang, Huang, Rong, Fan, Xingli, Ji, Lei, Cai, Damin, Liu, Xiaoxiang, Fu, Yixiu, Sun, Aihua, Feng, Chenzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127663/
https://www.ncbi.nlm.nih.gov/pubmed/35619949
http://dx.doi.org/10.3389/fnut.2022.909283
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author Jiang, Kankan
Fu, Xiaoliang
Huang, Rong
Fan, Xingli
Ji, Lei
Cai, Damin
Liu, Xiaoxiang
Fu, Yixiu
Sun, Aihua
Feng, Chenzhuo
author_facet Jiang, Kankan
Fu, Xiaoliang
Huang, Rong
Fan, Xingli
Ji, Lei
Cai, Damin
Liu, Xiaoxiang
Fu, Yixiu
Sun, Aihua
Feng, Chenzhuo
author_sort Jiang, Kankan
collection PubMed
description Xylooligosaccharides (XOS) are functional feed additives that are attracting growing commercial interest owing to their excellent ability to modulate the composition of the gut microbiota. The acid hydrolysis-based processing of xylan-containing materials has been proposed to represent a cost-effective approach to XOS preparation, with organic acids being preferable in this context. As such, in the present study, maleic acid was selected as a mild, edible organic acid for use in the hydrolysis of xylan to produce XOS. A response surface methodology (RSM) approach with a central composite design was employed to optimize maleic acid-mediated XOS production, resulting in a yield of 50.3% following a 15 min treatment with 0.08% maleic acid at 168°C. Under these conditions, the desired XOS degree of polymerization (2-3) was successfully achieved, demonstrating the viability of this using a low acid dose and a high reaction temperature to expedite the production of desired functional products. Moreover, as maleic acid is a relatively stable carboxylic acid, it has the potential to be recycled. These results suggest that dilute maleic acid-based thermal treatment of corncob-derived xylan can achieve satisfactory XOS yields, highlighting a promising and cost-effective approach to XOS production.
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spelling pubmed-91276632022-05-25 Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy Jiang, Kankan Fu, Xiaoliang Huang, Rong Fan, Xingli Ji, Lei Cai, Damin Liu, Xiaoxiang Fu, Yixiu Sun, Aihua Feng, Chenzhuo Front Nutr Nutrition Xylooligosaccharides (XOS) are functional feed additives that are attracting growing commercial interest owing to their excellent ability to modulate the composition of the gut microbiota. The acid hydrolysis-based processing of xylan-containing materials has been proposed to represent a cost-effective approach to XOS preparation, with organic acids being preferable in this context. As such, in the present study, maleic acid was selected as a mild, edible organic acid for use in the hydrolysis of xylan to produce XOS. A response surface methodology (RSM) approach with a central composite design was employed to optimize maleic acid-mediated XOS production, resulting in a yield of 50.3% following a 15 min treatment with 0.08% maleic acid at 168°C. Under these conditions, the desired XOS degree of polymerization (2-3) was successfully achieved, demonstrating the viability of this using a low acid dose and a high reaction temperature to expedite the production of desired functional products. Moreover, as maleic acid is a relatively stable carboxylic acid, it has the potential to be recycled. These results suggest that dilute maleic acid-based thermal treatment of corncob-derived xylan can achieve satisfactory XOS yields, highlighting a promising and cost-effective approach to XOS production. Frontiers Media S.A. 2022-05-10 /pmc/articles/PMC9127663/ /pubmed/35619949 http://dx.doi.org/10.3389/fnut.2022.909283 Text en Copyright © 2022 Jiang, Fu, Huang, Fan, Ji, Cai, Liu, Fu, Sun and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Jiang, Kankan
Fu, Xiaoliang
Huang, Rong
Fan, Xingli
Ji, Lei
Cai, Damin
Liu, Xiaoxiang
Fu, Yixiu
Sun, Aihua
Feng, Chenzhuo
Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy
title Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy
title_full Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy
title_fullStr Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy
title_full_unstemmed Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy
title_short Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy
title_sort production of prebiotic xylooligosaccharides via dilute maleic acid-mediated xylan hydrolysis using an rsm-model-based optimization strategy
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127663/
https://www.ncbi.nlm.nih.gov/pubmed/35619949
http://dx.doi.org/10.3389/fnut.2022.909283
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