TDP-43 Accumulation Within Intramuscular Nerve Bundles of Patients With Amyotrophic Lateral Sclerosis

IMPORTANCE: Degeneration of neuromuscular junctions and axons is considered an important aspect of the pathomechanism of amyotrophic lateral sclerosis (ALS). However, a mechanism including the role of transactive response DNA-binding protein 43 (TDP-43) in axons has not been pathologically clarified...

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Detalles Bibliográficos
Autores principales: Kurashige, Takashi, Morino, Hiroyuki, Murao, Tomomi, Izumi, Yuishin, Sugiura, Tomohito, Kuraoka, Kazuya, Kawakami, Hideshi, Torii, Tsuyoshi, Maruyama, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127711/
https://www.ncbi.nlm.nih.gov/pubmed/35604654
http://dx.doi.org/10.1001/jamaneurol.2022.1113

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