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Single‐Molecule Force Spectroscopy Reveals Stability of mitoNEET and its [2Fe2Se] Cluster in Weakly Acidic and Basic Solutions

The outer mitochondrial membrane protein mitoNEET (mNT) is a recently identified iron‐sulfur protein containing a unique Fe(2)S(2)(His)(1)(Cys)(3) metal cluster with a single Fe−N(His87) coordinating bond. This labile Fe−N bond led to multiple unfolding/rupture pathways of mNT and its cluster by ato...

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Detalles Bibliográficos
Autores principales: Nie, Jing‐Yuan, Song, Guo‐Bin, Deng, Yi‐Bing, Zheng, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127745/
https://www.ncbi.nlm.nih.gov/pubmed/35608094
http://dx.doi.org/10.1002/open.202200056