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The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective
Cell wall polysaccharides (CWPS) of seaweeds play crucial roles in mechanical shear resistance, cell-cell adhesion and the interactions with changeable marine environments. They have diverse applications in food, cosmetics, agriculture, pharmaceuticals and therapeutics. The recent boost of multi-omi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127767/ https://www.ncbi.nlm.nih.gov/pubmed/35620682 http://dx.doi.org/10.3389/fpls.2022.902823 |
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author | Shao, Zhanru Duan, Delin |
author_facet | Shao, Zhanru Duan, Delin |
author_sort | Shao, Zhanru |
collection | PubMed |
description | Cell wall polysaccharides (CWPS) of seaweeds play crucial roles in mechanical shear resistance, cell-cell adhesion and the interactions with changeable marine environments. They have diverse applications in food, cosmetics, agriculture, pharmaceuticals and therapeutics. The recent boost of multi-omics sequence analysis has rapidly progressed the mining of presumed genes encoding enzymes involved in CWPS biosynthesis pathways. In this review, we summarize the biosynthetic pathways of alginate, fucoidan, agar, carrageenan and ulvan in seaweeds referred to the literatures on published genomes and biochemical characterization of encoded enzymes. Some transcriptomic data were briefly reported to discuss the correlation between gene expression levels and CWPS contents. Mannuronan C-5 epimerase (MC5E) and carbohydrate sulfotransferase (CST) are crucial enzymes for alginate and sulfated CWPS, respectively. Nonetheless, most CWPS-relevant genes were merely investigated by gene mining and phylogenetic analysis. We offer an integrative view of CWPS biosynthesis from a molecular perspective and discuss about the underlying regulation mechanism. However, a clear understanding of the relationship between chemical structure and bioactivities of CWPS is limited, and reverse genetic manipulation and effective gene editing tools need to be developed in future. |
format | Online Article Text |
id | pubmed-9127767 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91277672022-05-25 The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective Shao, Zhanru Duan, Delin Front Plant Sci Plant Science Cell wall polysaccharides (CWPS) of seaweeds play crucial roles in mechanical shear resistance, cell-cell adhesion and the interactions with changeable marine environments. They have diverse applications in food, cosmetics, agriculture, pharmaceuticals and therapeutics. The recent boost of multi-omics sequence analysis has rapidly progressed the mining of presumed genes encoding enzymes involved in CWPS biosynthesis pathways. In this review, we summarize the biosynthetic pathways of alginate, fucoidan, agar, carrageenan and ulvan in seaweeds referred to the literatures on published genomes and biochemical characterization of encoded enzymes. Some transcriptomic data were briefly reported to discuss the correlation between gene expression levels and CWPS contents. Mannuronan C-5 epimerase (MC5E) and carbohydrate sulfotransferase (CST) are crucial enzymes for alginate and sulfated CWPS, respectively. Nonetheless, most CWPS-relevant genes were merely investigated by gene mining and phylogenetic analysis. We offer an integrative view of CWPS biosynthesis from a molecular perspective and discuss about the underlying regulation mechanism. However, a clear understanding of the relationship between chemical structure and bioactivities of CWPS is limited, and reverse genetic manipulation and effective gene editing tools need to be developed in future. Frontiers Media S.A. 2022-05-10 /pmc/articles/PMC9127767/ /pubmed/35620682 http://dx.doi.org/10.3389/fpls.2022.902823 Text en Copyright © 2022 Shao and Duan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Plant Science Shao, Zhanru Duan, Delin The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective |
title | The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective |
title_full | The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective |
title_fullStr | The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective |
title_full_unstemmed | The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective |
title_short | The Cell Wall Polysaccharides Biosynthesis in Seaweeds: A Molecular Perspective |
title_sort | cell wall polysaccharides biosynthesis in seaweeds: a molecular perspective |
topic | Plant Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127767/ https://www.ncbi.nlm.nih.gov/pubmed/35620682 http://dx.doi.org/10.3389/fpls.2022.902823 |
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