Echinocandins Localized to the Target-Harboring Cell Surface Are Not Degraded but Those Entering the Vacuole Are

[Image: see text] Echinocandin antifungal drugs have a broad spectrum of activities and excellent safety profiles. These agents noncompetitively inhibit the formation of the major polysaccharide component of the fungal cell wall, a reaction catalyzed by the membrane-bound β-glucan synthase (GS) prot...

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Detalles Bibliográficos
Autores principales: Jaber, Qais Z., Logviniuk, Dana, Yona, Adi, Fridman, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127807/
https://www.ncbi.nlm.nih.gov/pubmed/35404573
http://dx.doi.org/10.1021/acschembio.2c00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127807/
https://www.ncbi.nlm.nih.gov/pubmed/35404573
http://dx.doi.org/10.1021/acschembio.2c00060

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