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Mitochondrial DNA Instability in Mammalian Cells

SIGNIFICANCE: The small, multicopy mitochondrial genome (mitochondrial DNA [mtDNA]) is essential for efficient energy production, as alterations in its coding information or a decrease in its copy number disrupt mitochondrial ATP synthesis. However, the mitochondrial replication machinery encounters...

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Detalles Bibliográficos
Autores principales:	Carvalho, Gustavo, Repolês, Bruno Marçal, Mendes, Isabela, Wanrooij, Paulina H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127837/ https://www.ncbi.nlm.nih.gov/pubmed/34015960 http://dx.doi.org/10.1089/ars.2021.0091

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