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Unique SLC12A2-ROS1 fusion is associated with marked response to crizotinib in lung adenocarcinoma

Chromosomal rearrangements involving the c-ros oncogene 1 (ROS1) gene define a subset of non-small cell lung cancers highly sensitive to small-molecule tyrosine kinase inhibitors. However, little is known about the impact of different fusion partners on tyrosine kinase inhibitor efficacy. We herein...

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Detalles Bibliográficos
Autores principales: Ribeiro, Maurício Fernando Silva Almeida, Gadotti, Luiza Lara, Sacardo, Karina Perez, Lopes, Carlos Diego Holanda, Saddi, Rodrigo, Alessi, João Victor Machado, de Macedo, Mariana Petaccia, do Nascimento, Ellen Caroline Toledo, Testagrossa, Leonardo de Abreu, Katz, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9127844/
https://www.ncbi.nlm.nih.gov/pubmed/35619747
http://dx.doi.org/10.1177/2050313X221100407

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